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Green-lipped mussel extract may protect against muscle damage post-exercise

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New research conducted by researchers from the University of Indiana-Bloomington and published in the Journal of the International Society of Sports Nutrition, has found that green-lipped mussel extract can suppress certain markers of muscle damage and inflammation that usually increase during exercise.

The study set out to evaluate the effects of PCSO-524, a marine oil lipid and n-3 LC PUFA blend, derived from New Zealand green-lipped mussel on markers of muscle damage and inflammation following muscle-damaging exercise in untrained men.

32 untrained male subjects were randomly assigned 1,200mg per day of Pharmalink International’s PCSO- 524 or placebo for 26 days prior to a bout of downhill running, and continued for 96 hours following the exercise.

Compared to placebo, supplementation with the green-lipped mussel oil blend significantly reduced delayed onset muscle soreness at 72 and 96 hours post-muscle damaging exercise, and resulted in significantly less strength loss and provided a protective effect against joint range of movement loss at 96 hours afterwards. At 24 hours after the exercise perceived pain was significantly greater compared to baseline in the placebo group only.

The researchers concluded that supplementation with a marine oil lipid and n-3 LC PUFA blend derived from the New Zealand green lipped mussel, may represent a useful therapeutic agent for attenuating muscle damage and inflammation following muscle-damaging exercise.

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